Those are all correct; list updated. Fred is worth 10 bonus shots.

Close enough to a day:

Adding letters/number to answers as chosen by Random Number Generator. Letter (*) and number (#) patterns below. If there is a forward slash, the first name is the code name and the second name is the real name (for such characters I'll accept either name).  Not every number appears in this collage but every letter does. Obviously if a letter is revealed but not shown for a particular character, they don't have that letter in their name.

The next letter is an O.

Letters/numbers used so far: EFGHJKORT345

1. Comics; criminal; former classmate of two cast characters; Action Comics R**K ****E**E
4. Original; unrevealed; girlfriend of one villain who was killed by another *OE*
5. Comics; unwilling drug producer; powers related to his tears; Master Comics  THE *EE*ER
6. Original; university dean; ally of a hate group **RRE*
10. Comics; businessman; related to a reformed villain; The Flash  O*GOO* R*TH****
12. Original; cultist; become disillusioned with source of worship  O*****
16. Original; police detective; in sole appearance directed a main character to someone's office ****E
17. Original; unrevealed; mother of kidnap victim REG*** ********
18. Comics; criminal; insecure re: physical appearance; Batman Family **E** *E*T
19. Comics; warden; sold meta-humans to villain; The Flash: Iron Heights GREGOR* *O*FE
20. Comics; terrorist; leads group attempting to blow up city; Green Arrow *ERO**** ***E
21. Comics; crime lord; one of four remaining leaders in his org surviving after a purge; Green Arrow **R** *RO*ER**K
22. Comics; mayor; wounded by a bullet during a riot; Batman: Turning Points  *****E* *K***
23. Original; scientist; originally from 1925 but now time travelling; cast character G*** ****E*
24. Original; editor-in-chief; believed main character had gone bad **OTT E****
25. Comics; scientist turned criminal; infected by alien parasite; Firestorm **R***TE / R*** JO*E*
26. Original; criminal; member of China-based crime group  K*T** *HE*G
27. Original but related to comics based character; sheriff; abandoned daughter upon learning she was a lesbian  O***R RO***
29. Original; federal agent; electrocuted TO** K**
31. Original; drug dealer; drug his sold turned people into monsters JERR* ****ER
32. Original, but uses comics character as alias; businessman; half-brother of a main character *ORG** E*GE / T**-RHO
33. Original; engineer turned professor; murdered by a super-villain ******* K**G
34. Original; marine turned bodyguard/criminal; killed by a main character to save an ally **** K*O*
35. Original; would-be unwilling slave; daughter of #17 **** ********
36. Comics; unrevealed; murdered by her husband; New Teen Titans *OR** *H**E
37. Original; attorney; killed by a vigilante G** ****TO**
38. Original; computer engineer/programmer; used VR as a means of torture R**H*R* **TE*
39. Comics; military general; father of counterpart of a main character; Superman's Girl Friend, Lois Lane *** ***E (E*RTH-T**##)
40. Original; university professor; betrayed her sister **E*E ***
41. Original; unrevealed; given age, possible student at some point, otherwise none; son of a main character JO***
42. Original; assassin; committed suicide to avoid further interrogation THE **KE
46. Original; sheriff; active in 1925 THO*** *OO*
51. Comics; unrevealed; mother of hero active in the future; Green Arrow ***R* H**KE
52. Webseries (different first name); police department employee; super-villain's sister in law; Gotham Girls  *EE ***TH*
54. Comics; owner/leader of a branch of a company; father of a cast character; Superman Annual  **R**R*O ROJ**
55. Comics; bodyguard turned "church" leader; succeeded a super-villain in a comics tie-in; Animal Man ****TO* HOG*E
56. Original; unrevealed; possible housewife; mother of a main character *OROTH* HE**OO*
57. Original; criminal; henchman to a villain who is the son of a reformed villain ******ER
58. Original; alderman; kidnapped and killed by villain for revenge R**H*R* FOR*
60. Original; criminal; alcoholic who abused his ex-girlfriend ***H*** ***O**
61. Comics; firefighter turned arsonist; murdered people he felt had abandoned him; Detective Comics G*RF*E** *****
62. Original; security agent; helped keep a protest from going further out of control ***R*
64. Comics; criminal; could shrink objects; The All-New Atom ***RF*T*R / ****ERT R*****E
65. Original; chef (police officer in another timeline); killed in revenge for actions from temporary timeline *T**RT HO******
66. Original; student when last seen; friend/classmate of major character **RGO
67. Comics; bank robber; has psychic powers; Daring New Adventures of Supergirl *** / G***E **R*H
69. Original; unrevealed; drug addict, wife of major character ***R* R***RE*
70. Original; likely assassin; killed over 200 people T*GRE***
71. Comics but with different first name as comics version's first/last name taken by different character; unrevealed; was the wife of a major character; Showcase **** *OR**G
72. Original; unrevealed; part of family cheated out of life's savings  ER** *OORE
74. Comics, though comics version is unnamed; soldier; father of major villain; unsure, possible The Flash Secret Files and Origins J**E* *O*O*O*
75. Character's race based on single comics character; criminal *****E* HE**GR****TE
76. Comics characters use code name but none seem to be the basis of this character; criminal; prison escapee *H**ER*
77. Original; unrevealed; mother of major character *E***E *****
78. Comics; businessman/terrorist; part of a plan to rid the Earth of most of humanity; Green Arrow ***O *R**T*GE
79. Original; politician in some sort of position of power; invited major characters on opposing sides to be keynote speakers in a media summit. ***OR OF **T*O*** **T*
80. Original; medical doctor; treated main character for free in support of their actions *O*KH*RT
81. Original; pianist; from artificial reality GR***
82. Original; unrevealed; patient at major character's clinic ***TT**ER
83. Original; political strategist turned chief of staff; assisted in major character's political campaign **E* *****
84. Original; unrevealed; parent of major character **R* T*R***'* F*THER
85. Original; businessman; embezzled about $30 million from a pension plan **R*** RE**O**
86. Original; serial killer; drowned victims before dressing them up *O*****ER aka *ROKE* *O** K***ER / **RTO* **TH**
87. Original; CEO; from Markovia **E* T*RKO*
88. Original; criminal; helped rob seven banks in three states within two weeks *K*** *** / R**K*E JE*K***
89. Original; councilman; opposed a request from a major character, fearing for his city's survival J**-**
90. Original but related to character from comics; likely prince; sister was a major villain *R****
91. Original but deliberately made to look like unrelated Arrowverse character; mobster; from same artificial reality as #81 **G** FO**' H******
92. Comics; king; father of #90; Superman Family *** K**G / *R***
93. Imposter of character somewhat but not entirely based on comics; assassin; artificial lifeform **R* ****E (RO*OT)
94. Real person; prince; reincarnated after death KH*F*  [LOCKED; both remaining letters the same; characters found at time of locking: FGHJKORT345]
95. Original; unrevealed; daughter has alien pet *****'* F*TH*ER
96. Original but relative of character from comics; engineer; father of major character ***** *. R**K
97. Original; prison guard; brought in as part of prison reform effort  FE*TO*
98. Original; pilot; father of close friend of major character ***** ***O*E'* F*THER
99. Original; some sort of media employee; major character did compositions for him  H***H*
100. Original; drug dealer; stopped as part of an effort to show someone a better way in dealing with criminals **THO** *E***
101. Comics; unrevealed; wife of a villain; Deadshot ****E ***TO*
102. Original; crime boss; at attempt to kill him happened in an arena **KH*** *ETRO*
103. Real person; singer; this version wrote a song after seeing a character get abducted ***** *O**E
105. Comics; bar owner; some of his customers were killed in a weapons test; Lobo ** *R**E
106. Original; documentary director; accompanied major characters to Russia  KE*** H*RR**
108. Original; retail manager; major character briefly worked for him ***
109. Comics; former criminal of sorts; courted a major character; Superman *****T*K
110. Comics; cage fighter; fought main character in a match; Adventures of Superman *R**G*
112. Original apparently, though comics characters with same name have appeared; assassin; hired to kill a mayor *******R
114. Original; disc jockey/assassin; DJ work was for a major character *H**E
116. Original; ex-criminal; extra-terrestrial  OR****O *****
117. Comics; attorney; represented main character in trial; Showcase JE** *OR**G
118. Original; CEO/businessman/land baron; used company to swindle hundreds out of their homes and life savings **** H***
119. Original; councilman; tried to get a bribe from father of main character  HE*R* GOO****
121. Original; federal law enforcement agent; investigated main character ******* **T*O*
122. Original; student when last seen; history changed significantly due to the Crisis  KE*** **
124. Original; soldier (private); killed as part of a plan to frame someone in the theft of weapons *O*****
125. Original; time pirate; erased from history due to future deeds  K***E* *R****
126. Original but related to character from comics; in one timeline was a hero's adoptive father *H**K *****E
127. Original; toy shop worker; mother of a cast character **** **GO***
128. Original; unrevealed; with husband, acted as guardian for grandson after grandson's parents were killed T***O* *OORE'* GR****OTHER
129. Original; temporal agent; hypnotized during a performance review *E*TE*
130. Likely comics;  military general; taken hostage during weapons demonstration; All-American Men of War **O**
131. Comics (slightly different surname); criminal; can manipulate people's emotions; The Flash R****O* R***ER     / *O* ***O*O
132. Original; nightclub employee; made out with a guy has part of the latter's attempt to break up with his girlfriend *E***
133. Original; student; plays high school football ****O** TE*G*E
134. Comics, though names may or may not be the same; unrevealed; active as such in the Old West; Weird Western Tales *H**-*R*'* ##TH *E*T*R* RE*******T*O*
135. Comics; unrevealed; mother of a main character; Detective Comics G*** K**E
136. Comics; travel enforcement officer; has telepathy and other powers of the mind; Mister Terrific *R****TOR* / *O***** ****E
137. Original; medical doctor/slave trader; sent humans off world *****OR*** *O*TOR
138. Original; student; dated a cast character *H*** *O****
139. Original; fire chief; targeted by #61  R*****
140. Original; CEO/businessman; hired an assassin to kill bidders of a company he wished to own **RR* **TE*
141. Original; personal assistant; posed as his employer (a major villain) to help them escape another major villain ****E* **RK'* *****T**T
142. Original; restaurant employee; own name unknown but restaurant name refers to something you might find on a table at a restaurant T***E ***T HO*TE**
143. Original; real estate developer; people died in his buildings due to inadequate heating **** ***KE*
144. Original; career criminal; took over boyfriend's criminal business why he was incarcerated ******
147. Comics; board member; tried to use company owner's emails to ruin her reputation; Superman: The Man of Steel **RK *R**TRO*G
148. Original (real name), comics (aliases); vigilante; hero active in the future on a parallel Earth; Green Arrow GREE* *RRO* a.k.a. *O**OR H**KE /  JO** **GG*E, JR. (E*RTH-##)
149. Original; unrevealed; clubber who used drugs *ERO**** ***RK*
150. Original; criminal; injured himself shooting someone he didn't know had powers. *****E* **GGER
151. Comics character with different name; warrior; active in the 31th century in one future under a different name; Legion of Super-Heroes *E*T**E**E
152. Original; unrevealed; broke up with girlfriend for cheating on her E****
153. Real person; astronaut; real version still alive as of Feb 2022  FRE* H***E
154. Original; some sort of bearer (I can't be much more specific without revealing the answer); first of their kind (connected to other bearers)  F*R*T ***R*T TOTE* *E*RER
155. Comics but gender swapped (real names may or may not be similar); arsonist; briefly acquitted when issues arose in his trial but arrested again after another crime; Justice League Task Force HE*T *O*GER / ****O** *OO***G*
156. Original; high ranking fishing boat worker; brought a main character home after time away ***T***
157. Original; board member; killed by some sort of robotic tech *H**
158. Comics; businessman; took over a major character's body; Underworld Unleashed *ERO* [LOCKED; both remaining letters the same; characters found at time of locking: EFGHJKORT345]
159. Original; police officer; held captive for a time in another world ***** KOR*ER
160. Original mixed with mythology; coachman; replaced a Hindu god  K****E** / ***J**
162. Original; district attorney; represented a case against a main character *** *R****
163. Original; unrevealed, but likely student if any when last seen; father falsely charged with the murder of her mother **** *E****
164. Original; student when last seen; star high school quarterback J*KE HO*E**
165. Original; criminal; killed by his boss  RO*ERT ****OR
166. Comics; police detective; cast character and romantic interest to another cast character; Superman **GG*E ****ER
167. Original; Unrevealed, possible criminal; prisoner on a ship  HE**R**K *O* *R***
169. Comics (real names may or may not be the same), cryogeneticist, bartender, criminal; romantic interest to cast character; The Flash Annual *H********E / ***K *****E
170. Original; deputy sheriff; in one timeline investigated #122's death **E*E**
173. Original but related to character from comics; unrevealed; twin sister of a key recurring character *E*
174. Original; terrorist; tried to stop the launch of a VR service *** ****H**E
175. Original; marine biologist; widow of the counterpart of a super-villain T**** ****E*
176. Original but surname is a nod to real person; babysitter for the child of a super-villain **E**ER
177. Original; judge; presided over main character trial  H**KER***
178. Original but successor to comics based character; first and last names are nods to two different real people; collections officer; can manipulate people's emotions R****O* R***ER #.# / **RR*E **TE*
180. Original; nun turned singer/guitarist; part of a band that a cast character is also part of G****
182. Original; fence; arrested during the sale of a stolen jewel ****RE ***OTT
184. Comics; board member, businessman; saved from assassination attempt by a main character; Steel TO* *E*TO*
185. Original; lawyer turned criminal; sought revenge against the lawyer firm *RTH*R ******
186. Movie; witch; survived her reality being destroyed by the Crisis; Supergirl *E*E** (E*RTH-T**##)
187. Comics; wrestler turned criminal; other than a fang, thus far only seen in photo; Detective Comics K***ER *RO* / ****O* JO*E*
188. Original; unrevealed; extra-terrestrial *R***
189. Comics; student; aged at accelerated rate; The Flash: The Fastest Man Alive GR*FF** GRE*
190. Original; criminal; snapped after family killed in a mall J**E* E*****
191. Original but surname possible nod to real person; physician; often helped main character and allies E**** **H**RT*
193. Original; orphanage head, foster mother; raised a major character **R* ****ER
194. Original; bowler; extra-terrestrial or at least operates outside of Earth *ER*E THE **R*E
195. Original; police sergeant; briefed main characters on missions  F. ***G**E*
196. Original; criminal; attended crime family gathering *ERG*O E****O**
197. Original; probable student; dated a cast character for a time  E****
198. Original but related to character based on comics and is more or less a stand-in for a code name she apparently didn't use; bank robber; part of family of criminals *R*. RE*TO*
199. Original; medical doctor; treated a cast character  K*****
200. Original; nurse; worked for cast character ***
202. Original; bartender; ex-girlfriend of cast character **R**
203. Original; unrevealed, possible student when last seen; could heal mortal injuries  FER****O
207. Original; soldier; helped brother steal weaponry from military base  E*R* **R***
208. Real person (at least going by first name); unrevealed; sought autograph from heroes **R*
209. Comics; energy source; has strong connection to a major character; The Flash **EE* FOR*E
210. Original, though shares name with comics character; unrevealed; once erroneously believed to have killed a major character *KE*
211. Original; bank robber; sent to steal for comics based villain *ERTO [LOCKED; characters found at time of locking: EFGHJKORT345]
212. Original; criminal; prisoner in other dimensional realm ***R
214. Original; therapist for main character ***E*
215. Original but related to character from comics; fire chief; wife has launched campaign for mayor; cast character   K*** ***H**G
216. Original; religious figure (can't say what kind without revealing name), possible assassin; officiates rituals and ceremonies THE *R*E*TE**
217. Original; sheriff; lived in Oregon *U* E****O*
218. Original though code name used by comics characters; crime lord; wanted to create coalition of crime gangs  TO**** *H*R**
219. Original; criminal; joined major villain's army  R***E*
220. Original, though nicknamed by another character after a literary character; criminal of sorts, though possibly not by occupation; tormented major character for years ***E* **RT*R**HT
222. Original; pirate; lover of famous pirate ***E **EE*
223. Original; film director; did documentary on main character **R*** *E*O**T*
224. Comics; outlaw; responsible for town's destruction; Weird Western Tales **E*T** T*R*****
225. Comics; student; related to a main character; Convergence: Superman JO**TH** KE*T (*O*T-*R***)
226. Original; unrevealed; posed as treasure seeker in VR reality  TRE***RE H**TER T**** / *O***E ***KER
228. Original; crime family consigliere; killed by boss' daughter **** *****T*
229. Original; student; accidentally electrocuted by unconscious friend **R** K**
230. Original but distant relative of comics based character; robotics engineer; seen in 2147 *R**E
231. Original; federal agent posing as accountant; killed by villainous cast character J**K*O* K******H
232. Original; government agent; from China but killed in New Zealand *E* ***G
233. Original; waitress; sister-in-law and ex-girlfriend of major character **R** **GG*E
234. Original; criminal; broken out of jail by super-villain girlfriend **** **R*ER
235. Comics, though possibly created for earlier show; police task force officer; romantically involved with super-villain; Batman RE*EE *O*TO**
236. Original; high school coach; allowed main character to be assistant coach G***E*
237. Comics; police commissioner; disapproved of main character's actions; Green Arrow *R*** ***O*ER*O
238. Mostly comics (real name original but related to character from comics); bank robber; son of #198 **E / K**E RE*TO*
239. Original; unrevealed; husband of long recurring character RO*  [LOCKED; characters found at time of locking: EFGHJKORT345]
240. Comics (comics version has different surname); unrevealed; son of cast character; Adventures of Superman **** FO*TER
241. Comics (comics version has different surname); legal aid attorney; was the best friend of a cast character; Green Arrow  JO**** *E ** *EG*
242. Comics; high ranking military officer; trained a main character; 52 **O FE* G**O*G
243. Comics; mobster/money launderer, nightclub manager; managed the nightclub on behalf of a super-villain; Detective Comics JO**** ****T**O
244. Original; SWAT officer turned bodyguard; briefly replaced a major character in job  RO* **OTT
245. Original; federal agent; possessed by villain based on comics hero  *O*O***
246. Earlier version of character; earlier version has code name from comics that this version doesn't share; head of security, criminal; killed by anti-matter RE*E R***RE* (E*RTH-#)
247. Comics; gangster; can turn his body into a specific element GO**F**E / KE*TH
248. Original; unrevealed; mother of #122 *** **
249. Comics; trivia night host; comics version is a major villain; Action Comics  O***** *OO***
251. Real person; shogun; died ten years prior to real world version  TOK*G*** *E**T**
252. Original; high priestess; prisoner whose name was used for prison   J***** KO* RO**
253. Original; board member; got major character ousted from company they were running *E****
255. Original; unrevealed; lives in a Maritimes city *EGG* ****O*
256. Original; shopkeeper; active in the near future  FE***
257. Comics (somewhat different name); assassin; second in command in her organization; Batwoman: Rebirth  T*T****
258. Comics; military Lieutenant Colonel working for major character; Human Defense Corps  RE*O RO*ETT*
259. Original; unrevealed; father of #122 **O** **
261. Original; criminal turned boxer; wrongly suspected of being a super-villain  F**T / *HR** *E**O*K
262. Comics but different name; hitman; hired to spy on main character; Superman ***** F*G*E*T**
263. Earlier show (different real name); drug dealer; ex-lover of main character; Batman: The Animated Series **** *O** / **GE****E **RT**
264. Original; bank robber; has fire powers ER*K FR*E
265. Comics; apparent criminal; can generate acid; Action Comics **** ***TER / *H**** ***TER
266. Comics (comics version unnamed); unrevealed; ex-mistress of #313; unsure, possibly New Year's Evil: Prometheus ****** *E*T**E**
267. Original; unrevealed, possibly none; engaged to a guy but secretly in love with a woman **. *******R
268. Original; probably none so far, possibly student; foster daughter of major characters  E**E
270. Original; parole officer for main character ***** *TE*E**
271. Original; member of resistance group; extra-terrestrial *'KE**
272. Comics; probably criminal; extra-terrestrial convict; Superman **RTO*
273. Original; car thief who claimed that a cast character was trying to steal his car  E**
274. Original; soldier; father of cast character J**E* J**K*O*
275. Original; soldier turned leader of vigilante group inspired by main character *G***
276. Comics; toy manufacturing company owner; ex-boss of super-villain; Action Comics *HE*TER ***HO*T*
277. Original; senator with an interest in extra-terrestrials  GR***ERR*
278. Original; EMT; could swap people's DNA *E*T**G *O**T / **TTHE* K**
279. Original; attorney; did pro-bono work for compAny major character worked at ****T****
280. Comics; personal physician for major villain; Superman's Pal, Jimmy Olsen ****E* *O*O***
281. Original; philanthropist/clinic owner; wife of major character, mainly seen in photo RE*E*** *ER***
283. Real person; student when last seen; likely later an attorney, philanthropist, and civic leader; former student of major character ******* G*TE*, *R.
286. Comics; police detective; former work partner of major character; Green Arrow and Black Canary ***** H**TO*
287. Original; influencer; disfigured subsequent to cosmetic surgery ****ER** *R*GHT
288. Comics; Russian federal agent; investigated by an American agency; Superman: Red Son **OTR RO**O*
289. Comics; journalist; operated in a different city pre- and post-Crisis; Adventures of Superman RO* TRO**E
290. Comics but gender swapped and comics version's real name is unknown; drug dealer; can manipulate time; Showcase T*RT*E # / FR*** *O**KO*
291. Original; criminal/double agent; acted as recruiter for her actual organization **** F****
292. Original; very high ranking poiltician; predecessor killed in alien invasion ***** *R***E*
293. Comics (comics version has different first name); criminal; counterpart of cast character's brother; Justice League of America's Vibe  R**T*RE / ***TE R**O* (E*RTH-#)
294. Earlier character this continuity; none; VR version of cast character **E* ****ER* (O****** ***T****)
295. Original; banker; saved from building that was blown up  G*R*
296. Original; football coach; hid that a player has brain damage and was using steroids K*RT *O*OH*E
297. Original; mercenary; worked for cast character's mother ****E **K***E*
298. Comics but gender swapped thus real first name different; mechanical engineer turned criminal; uses robotic creatures; The Atom **G-E*E* *****T a.k.a. **EE* *EE / *R*E **R***
299. Comics; assassin/black ops agent; deserted federal agency she used to work for; Detective Comics  O*** *****
301.  Somewhat based on comics (gender swapped), though another character has the comics version's abilities; quantum engineer/CEO; was replaced by a doppelgänger who posed as her; Animal Man  E** ******O*H
302. Original; police officer; betrayed his PD to a super-villain JO*E*
303. Original; student; wore homemade costumes based on main character *****
305. Original; high school student seeking university admission HE*R* *E****
306. Possible gender swapped version of character from earlier show; biomedical engineer, CEO; mother of cast character; The Flash (1990-1991 series) **R** T***H***ER
307. Comics; criminal; wrongly imprisoned for false confession; Supergirl **R**R / ***H*E* ***R
308. Original; mixed martial arts fighter; affected by a totem being activated *GOR *T*RRO*
309. Original; waitress; dropped food and drinks after bumping into co-worker  TR***
310. Original; singer; from Old West *O**O* **RR*TOR
311. Original; computer hacker; seduced by someone who killed him  K*R** **TE*
312. Original; fence; tried to steal from jewel thief **** *ERE***K
313. Comics (but this name not used in comics); CEO; masterminded an outbreak of tuberculosis; Vigilante  J**T** *****O*R*E
314. Comics; unrevealed if applicable; demonic rival to cast character; Hellblazer *****R****
315. Original; criminal; worked for comics-based villain  E***E *****K
316. Original; museum curator; super-villain stole necklace she had obtained permission to exhibit *O*****
317. Original; maid; murdered by employer  G***** *E*E**KTO*
318. Original; shop owner; aunt of super-villain ***E**
319. Original; drug dealer; sold drugs to cast character  JOR*** KER*
320. Original; artifacts collector; attacked by super-villain **R**TO*H ***K*
321. Original; unrevealed; possible professional fighter; part of super-villain's fight club *****
322. Original; reverend; arrested villager accused of being a witch **R*O**
323. Original; judge; helped send prisoners to death row regardless of guilt or innocence  R***O** ****ER**K
324. Original; unrevealed; was once a potential date for cast character via dating ap *HR** H***ER
325. Likely comics (not DC), different surname; probable student when last seen; went drag racing with boyfriend; Pep Comics *ETT* *E**ER
326. Original; military sergeant; part of army strike team **TE*
327. Original; adventurer; current cast character **OO*ER / E**ER**** *R**
328. Original; asylum nurse; informed by main and other cast character she was in danger but she realized they weren't entirely telling the truth  T****
329. Original; some sort of information provider; member of a shadow organization *E***TH** *E**E*GER
331. Original; criminal agent; leader of group within a group ****RE*
333. Original; criminal; prison bunk mate for recurring character *O TR****
337. Original; criminal/car workshop owner; killed by someone he tried to blackmail ****E* **RGE
338. Original; serial killer; her son was intially believed by heroes to be the killer *RO* **GHT *****ER / K*TH* *E*ER*
339. Comics; bank robber/terrorist; electricity powers; All-Star Squadron *E*TH*O*T / J*KE ****O**
340. Comics; high priestess; Egyptian who died thousands of years ago; Flash Comics *H**-*R*
341. Comics but spelled slightly differently; village leader; ancestor of a major character; Hellblazer KO**TE*T**
342. Original; probable student when last seen; boyfriend of  #325  TO*** F***ER
343. Comics; jewel thief; bonded with alien symbiote; Action Comics *E**GER*E / ***E** FERRER
344. Original; unrevealed; father of #255  TO***
345. Original; mayor; killed by hero's imposter *E*** ***T*E
346. Original; unrevealed; asked reporters to help locate missing son *H*RO* *O*E**
347. Original but related to character from comics; physics professor/philanthropist/criminal/engineering professor; wife of major villain  **R***E *E*OE
348. Original; scullery maid; lover of #267 E**E*
349. Comics but gender swapped, so slightly different first name; physical therapist; divorced from cast character; Spectre **** HO*T
350. Original; police technician; required to review footage involving main character  KE*TO*
351. Original; prison officer; was fired **RR* *H*****
352. Original; high ranking military officer/government agent/criminal; watched cage fight ***E* **RO*
353. Comics, though heavily changed; bodyguard/criminal; arrested for murder; World's Finest Comics **KO*
354. Original; unrevealed; #274's wife JEFFER*O* J**K*O*'* *OTHER
355. Original, though name might be a nod to two real life people; mayor; surname may refer to actor who was in another Arrowverse show GEORGE *E**
356. Original; unrevealed; was devastated when ex-wife was murdered ***R*E* EKE*
357. Original; criminal; worked for two different bosses (not concurrently) GREG O**OR*E
358. Original; crime boss employee; killed by boss' daughter **** *O****
359. Original; criminal; part of Chinese crime family ** KH*** H**
360. Comics, though different but similar real first name; photographer/thief; drawn to shiny objects; The Man of Steel **G**E / **RGOT
361. Original; scientist; tasked to recreate a virus  RO**RT *O*G
362. Original; member of secret, arguably criminal organization; friend turned enemy of major character ***** *R**E
363. Comics; hypnotist; worked for major villains; Teen Titans  E**G** / E*E*** RH**E
364. Original; soldier/mercenary; hired to bomb waterfront **OO***ORT / RO*ERT ***O**
366. Original; student; helped beat up cast characters  T**** R***
367. Original; reporter; cast character ******* *E*

Added more letters that I had overlooked before.

Added a few letters I had overlooked.

If a "name" begins with U, the "first name" might be "Unnamed"

Locked letters:
#158
#211
#239

Other characters who should now be easy to identify include:
#84 (if familiar with the series in question)
#94
#225
#247 (if familiar with the comics)
#289 (if familiar with the comics)
#298
#354
#364 (if familiar with the comics)

 

Locked characters:
#89
#97
#158
#176
#210
#211
#239
#273
#348
#350

Other characters who should now be easy to identify include:
#84 (if familiar with the series in question)
#94
#225
#247 (if familiar with the comics)
#289 (if familiar with the comics)
#298
#354
#364 (if familiar with the comics)

 

Adding letters/number to answers as chosen by Random Number Generator. Letter (*) and number (#) patterns below. If there is a forward slash, the first name is the code name and the second name is the real name (for such characters I'll accept either name).  Not every number appears in this collage but every letter does. Obviously if a letter is revealed but not shown for a particular character, they don't have that letter in their name.

The next numbers and letters, in order, are 0 (zero), 9, D, 8.

Letters/numbers used so far: DEFGHJKLORT345790

1. Comics; criminal; former classmate of two cast characters; Action Comics R**K **L*E**E
4. Original; unrevealed; girlfriend of one villain who was killed by another *OE*
5. Comics; unwilling drug producer; powers related to his tears; Master Comics  THE *EE*ER
6. Original; university dean; ally of a hate group **RRE*
10. Comics; businessman; related to a reformed villain; The Flash  O*GOOD R*TH****
12. Original; cultist; become disillusioned with source of worship  OL****
16. Original; police detective; in sole appearance directed a main character to someone's office *DD*E
17. Original; unrevealed; mother of kidnap victim REG*** **LL****
18. Comics; criminal; insecure re: physical appearance; Batman Family DUEL* DE*T
19. Comics; warden; sold meta-humans to villain; The Flash: Iron Heights GREGOR* *OLFE
20. Comics; terrorist; leads group attempting to blow up city; Green Arrow *ERO**** D*LE
21. Comics; crime lord; one of four remaining leaders in his org surviving after a purge; Green Arrow **RU* *RODER**K
22. Comics; mayor; wounded by a bullet during a riot; Batman: Turning Points  ***H*EL *K***
23. Original; scientist; originally from 1925 but now time travelling; cast character G*** D***E*
24. Original; editor-in-chief; believed main character had gone bad **OTT E****
25. Comics; scientist turned criminal; infected by alien parasite; Firestorm **R***TE / RUD* JO*E*
26. Original; criminal; member of China-based crime group  K*T*U *HE*G
27. Original but related to comics based character; sheriff; abandoned daughter upon learning she was a lesbian  O***R ROD**
29. Original; federal agent; electrocuted TO** K**
31. Original; drug dealer; drug his sold turned people into monsters JERR* **LLER
32. Original, but uses comics character as alias; businessman; half-brother of a main character *ORG** E*GE / T*L-RHO
33. Original; engineer turned professor; murdered by a super-villain  L**D*** K**G
34. Original; marine turned bodyguard/criminal; killed by a main character to save an ally ***L K*O*
35. Original; would-be unwilling slave; daughter of #17 **** **LL****
36. Comics; unrevealed; murdered by her husband; New Teen Titans DOR** *H**E
37. Original; attorney; killed by a vigilante GU* ****TO**
38. Original; computer engineer/programmer; used VR as a means of torture R**H*RD **TE*
39. Comics; military general; father of counterpart of a main character; Superman's Girl Friend, Lois Lane *** L**E (E*RTH-TU*##)
40. Original; university professor; betrayed her sister **E*E **L
41. Original; unrevealed; given age, possible student at some point, otherwise none; son of a main character JO***
42. Original; assassin; committed suicide to avoid further interrogation THE **KE
46. Original; sheriff; active in 1925 THO*** *OOD
51. Comics; unrevealed; mother of hero active in the future; Green Arrow **DR* H**KE
52. Webseries (different first name); police department employee; super-villain's sister in law; Gotham Girls  DEE ***TH*
54. Comics; owner/leader of a branch of a company; father of a cast character; Superman Annual  *ER**RDO ROJ**
55. Comics; bodyguard turned "church" leader; succeeded a super-villain in a comics tie-in; Animal Man *L**TO* HOGUE
56. Original; unrevealed; possible housewife; mother of a main character DOROTH* HE**OOD
57. Original; criminal; henchman to a villain who is the son of a reformed villain **L**DER
58. Original; alderman; kidnapped and killed by villain for revenge R**H*RD FORD
60. Original; criminal; alcoholic who abused his ex-girlfriend ***H*EL ***O**
61. Comics; firefighter turned arsonist; murdered people he felt had abandoned him; Detective Comics G*RF*ELD L****
62. Original; security agent; helped keep a protest from going further out of control ***R*
64. Comics; criminal; could shrink objects; The All-New Atom D**RF*T*R / **L*ERT RU*D**E
65. Original; chef (police officer in another timeline); killed in revenge for actions from temporary timeline *TU*RT HOL****
66. Original; student when last seen; friend/classmate of major character **RGO
67. Comics; bank robber; has psychic powers; Daring New Adventures of Supergirl *** / G**LE **R*H
69. Original; unrevealed; drug addict, wife of major character  L*UR* R***RE*
70. Original; likely assassin; killed over 200 people T*GRE***
71. Comics but with different first name as comics version's first/last name taken by different character; unrevealed; was the wife of a major character; Showcase **** LOR**G
72. Original; unrevealed; part of family cheated out of life's savings  ER** *OORE
74. Comics, though comics version is unnamed; soldier; father of major villain; unsure, possible The Flash Secret Files and Origins J**E* *OLO*O*
75. Character's race based on single comics character; criminal  U****ED HELLGR****TE
76. Comics characters use code name but none seem to be the basis of this character; criminal; prison escapee *H**ER*
77. Original; unrevealed; mother of major character DE***E D****
78. Comics; businessman/terrorist; part of a plan to rid the Earth of most of humanity; Green Arrow **LO *R**T*GE
79. Original; politician in some sort of position of power; invited major characters on opposing sides to be keynote speakers in a media summit. ***OR OF **T*O**L **T*
80. Original; medical doctor; treated main character for free in support of their actions LO*KH*RT
81. Original; pianist; from artificial reality GR*D*
82. Original; unrevealed; patient at major character's clinic ***TT**ER
83. Original; political strategist turned chief of staff; assisted in major character's political campaign *LE* D****
84. Original; unrevealed; parent of major character **R* T*R***'* F*THER
85. Original; businessman; embezzled about $30 million from a pension plan **R*U* RED*O*D
86. Original; serial killer; drowned victims before dressing them up DOLL**KER aka *ROKE* DOLL K*LLER / **RTO* **TH**
87. Original; CEO; from Markovia *LE* T*RKO*
88. Original; criminal; helped rob seven banks in three states within two weeks *KULL *** / R**K*E JE*K***
89. Original; councilman; opposed a request from a major character, fearing for his city's survival JUL-U* [LOCKED; characters found at time of locking: EFGHJKLORTU3457]
90. Original but related to character from comics; likely prince; sister was a major villain *R**L*
91. Original but deliberately made to look like unrelated Arrowverse character; mobster; from same artificial reality as #81 D*G** FO**' HU****D
92. Comics; king; father of #90; Superman Family **D K**G / *R***
93. Imposter of character somewhat but not entirely based on comics; assassin; artificial lifeform **R* L***E (RO*OT)
94. Real person; prince; reincarnated after death KH*F* [LOCKED; both remaining letters the same; characters found at time of locking: FGHJKORT345]
95. Original; unrevealed; daughter has alien pet *L***'* F*TH*ER
96. Original but relative of character from comics; engineer; father of major character *U*** *. RU*K
97. Original; prison guard; brought in as part of prison reform effort  FELTO* [LOCKED; characters found at time of locking: EFGHJKLORTU3457]
98. Original; pilot; father of close friend of major character ***D* ***O*E'* F*THER
99. Original; some sort of media employee; major character did compositions for him  H***H*
100. Original; drug dealer; stopped as part of an effort to show someone a better way in dealing with criminals **THO** *E***
101. Comics; unrevealed; wife of a villain; Deadshot *U**E L**TO*
102. Original; crime boss; at attempt to kill him happened in an arena **KH**L *ETRO*
103. Real person; singer; this version wrote a song after seeing a character get abducted D***D *O**E
105. Comics; bar owner; some of his customers were killed in a weapons test; Lobo *L *R**E
106. Original; documentary director; accompanied major characters to Russia  KE*** H*RR**
108. Original; retail manager; major character briefly worked for him **L
109. Comics; former criminal of sorts; courted a major character; Superman *****TLK
110. Comics; cage fighter; fought main character in a match; Adventures of Superman DR**G* [LOCKED; all remaining letters the same; characters found at time of locking: DEFGHJKLORT345790]
112. Original apparently, though comics characters with same name have appeared; assassin; hired to kill a mayor *****T*R
114. Original; disc jockey/assassin; DJ work was for a major character *H**E
116. Original; ex-criminal; extra-terrestrial  ORL**DO D****
117. Comics; attorney; represented main character in trial; Showcase JE** LOR**G
118. Original; CEO/businessman/land baron; used company to swindle hundreds out of their homes and life savings *D** HU*T
119. Original; councilman; tried to get a bribe from father of main character  HE*R* GOOD***
121. Original; federal law enforcement agent; investigated main character *****D* **T*O*
122. Original; student when last seen; history changed significantly due to the Crisis  KE*** L*
124. Original; soldier (private); killed as part of a plan to frame someone in the theft of weapons *OLL***
125. Original; time pirate; erased from history due to future deeds  K**LE* DRU***
126. Original but related to character from comics; in one timeline was a hero's adoptive father *HU*K *****E
127. Original; toy shop worker; mother of a cast character **** **GO***
128. Original; unrevealed; with husband, acted as guardian for grandson after grandson's parents were killed T**LO* *OORE'* GR**D*OTHER
129. Original; temporal agent; hypnotized during a performance review DE*TEL [LOCKED; characters found at time of locking: DEFGHJKLORT345790]
130. Likely comics;  military general; taken hostage during weapons demonstration; All-American Men of War *LOUD [LOCKED; characters found at time of locking: DEFGHJKLORT345790]
131. Comics (slightly different surname); criminal; can manipulate people's emotions; The Flash R****O* R**DER     / RO* ***OLO
132. Original; nightclub employee; made out with a guy has part of the latter's attempt to break up with his girlfriend *E***
133. Original; student; plays high school football **L*O** TE*GUE
134. Comics, though names may or may not be the same; unrevealed; active as such in the Old West; Weird Western Tales *H**-*R*'* #9TH *E*TUR* RE*******T*O*
135. Comics; unrevealed; mother of a main character; Detective Comics G*** K**E
136. Comics; travel enforcement officer; has telepathy and other powers of the mind; Mister Terrific *R****TOR* / DO***** L***E
137. Original; medical doctor/slave trader; sent humans off world ***LDOR*** DO*TOR
138. Original; student; dated a cast character *H*** *OL***
139. Original; fire chief; targeted by #61  R*****
140. Original; CEO/businessman; hired an assassin to kill bidders of a company he wished to own **RR* **TEL
141. Original; personal assistant; posed as his employer (a major villain) to help them escape another major villain D***E* D*RHK'* *****T**T
142. Original; restaurant employee; own name unknown but restaurant name refers to something you might find on a table at a restaurant T**LE **LT HO*TE**
143. Original; real estate developer; people died in his buildings due to inadequate heating J*H* ***KEL
144. Original; career criminal; took over boyfriend's criminal business why he was incarcerated ******
147. Comics; board member; tried to use company owner's emails to ruin her reputation; Superman: The Man of Steel D*RK *R**TRO*G
148. Original (real name), comics (aliases); vigilante; hero active in the future on a parallel Earth; Green Arrow GREE* *RRO* a.k.a. *O**OR H**KE /  JOH* D*GGLE, JR. (E*RTH-##)
149. Original; unrevealed; clubber who used drugs *ERO**** ***RK*
150. Original; criminal; injured himself shooting someone he didn't know had powers. U****ED *UGGER
151. Comics character with different name; warrior; active in the 31th century in one future under a different name; Legion of Super-Heroes *E*T*LE**E
152. Original; unrevealed; broke up with girlfriend for cheating on her E**L*
153. Real person; astronaut; real version still alive as of Feb 2022  FRE* H***E
154. Original; some sort of bearer (I can't be much more specific without revealing the answer); first of their kind (connected to other bearers)  F*R*T ***R*T TOTE* *E*RER
155. Comics but gender swapped (real names may or may not be similar); arsonist; briefly acquitted when issues arose in his trial but arrested again after another crime; Justice League Task Force HE*T *O*GER / LU**OU* *OOL*DGE
156. Original; high ranking fishing boat worker; brought a main character home after time away ***T***
157. Original; board member; killed by some sort of robotic tech *H*L
158. Comics; businessman; took over a major character's body; Underworld Unleashed *ERO* [LOCKED; both remaining letters the same; characters found at time of locking: EFGHJKORT345]
159. Original; police officer; held captive for a time in another world D**** KOR*ER
160. Original mixed with mythology; coachman; replaced a Hindu god  K***DE** / *U*J**
162. Original; district attorney; represented a case against a main character *** *R***D
163. Original; unrevealed, but likely student if any when last seen; father falsely charged with the murder of her mother **** DE*L**
164. Original; student when last seen; star high school quarterback J*KE HO*ELL
165. Original; criminal; killed by his boss  RO*ERT ***LOR
166. Comics; police detective; cast character and romantic interest to another cast character; Superman **GG*E ****ER
167. Original; Unrevealed, possible criminal; prisoner on a ship  HE*DR**K *O* *R***
169. Comics (real names may or may not be the same), cryogeneticist, bartender, criminal; romantic interest to cast character; The Flash Annual *H*LL*L***E / ***K *L***E
170. Original; deputy sheriff; in one timeline investigated #122's death *LE*E**
173. Original but related to character from comics; unrevealed; twin sister of a key recurring character *E*
174. Original; terrorist; tried to stop the launch of a VR service *** ****H**E
175. Original; marine biologist; widow of the counterpart of a super-villain T**** L**DE*
176. Original but surname is a nod to real person; babysitter for the child of a super-villain *UELLER  [LOCKED; characters found at time of locking: EFGHJKLORTU3457]
177. Original; judge; presided over main character trial  H**KER*O*
178. Original but successor to comics based character; first and last names are nods to two different real people; collections officer; can manipulate people's emotions R****O* R**DER #.0 / **RR*E **TE*
180. Original; nun turned singer/guitarist; part of a band that a cast character is also part of G*LL*
182. Original; fence; arrested during the sale of a stolen jewel *L**RE ***OTT
184. Comics; board member, businessman; saved from assassination attempt by a main character; Steel TO* *E*TO*
185. Original; lawyer turned criminal; sought revenge against the lawyer firm *RTHUR **LL**
186. Movie; witch; survived her reality being destroyed by the Crisis; Supergirl *ELE** (E*RTH-TUD#7)
187. Comics; wrestler turned criminal; other than a fang, thus far only seen in photo; Detective Comics K*LLER *RO* / ***LO* JO*E*
188. Original; unrevealed; extra-terrestrial *R***
189. Comics; student; aged at accelerated rate; The Flash: The Fastest Man Alive GR*FF** GRE*
190. Original; criminal; snapped after family killed in a mall J**E* EDLU*D
191. Original but surname possible nod to real person; physician; often helped main character and allies EL*** **H**RT*
193. Original; orphanage head, foster mother; raised a major character **R* ****ER
194. Original; bowler; extra-terrestrial or at least operates outside of Earth *ER*E THE *UR*E
195. Original; police sergeant; briefed main characters on missions  F. ***G*LE*
196. Original; criminal; attended crime family gathering *ERG*O E****O**
197. Original; probable student; dated a cast character for a time  EL***
198. Original but related to character based on comics and is more or less a stand-in for a code name she apparently didn't use; bank robber; part of family of criminals *R*. RE*TO*
199. Original; medical doctor; treated a cast character  K**L**
200. Original; nurse; worked for cast character ***
202. Original; bartender; ex-girlfriend of cast character D*RL* * [LOCKED; both remaining letters the same; characters found at time of locking: DEFGHJKLORT345790]
203. Original; unrevealed, possible student when last seen; could heal mortal injuries  FER***DO
207. Original; soldier; helped brother steal weaponry from military base  E*R* **R***
208. Real person (at least going by first name); unrevealed; sought autograph from heroes **R*`
209. Comics; energy source; has strong connection to a major character; The Flash **EED FOR*E
210. Original, though shares name with comics character; unrevealed; once erroneously believed to have killed a major character *KEL [LOCKED; characters found at time of locking: EFGHJKLORTU3457]
211. Original; bank robber; sent to steal for comics based villain *ERTO [LOCKED; characters found at time of locking: EFGHJKORT345]
212. Original; criminal; prisoner in other dimensional realm ***R
214. Original; therapist for main character **LE*
215. Original but related to character from comics; fire chief; wife has launched campaign for mayor; cast character K*L* *U*H**G
216. Original; religious figure (can't say what kind without revealing name), possible assassin; officiates rituals and ceremonies THE *R*E*TE**
217. Original; sheriff; lived in Oregon *UD ELL**O*
218. Original though code name used by comics characters; crime lord; wanted to create coalition of crime gangs  TO**** *HUR**
219. Original; criminal; joined major villain's army  R***ED
220. Original, though nicknamed by another character after a literary character; criminal of sorts, though possibly not by occupation; tormented major character for years ***EL **RT*R*GHT
222. Original; pirate; lover of famous pirate ***E *UEE*
223. Original; film director; did documentary on main character **R*** *E*O**T*
224. Comics; outlaw; responsible for town's destruction; Weird Western Tales *UE*T** TUR**ULL
225. Comics; student; related to a main character; Convergence: Superman JO**TH** KE*T (*O*T-*R***)
226. Original; unrevealed; posed as treasure seeker in VR reality  TRE**URE HU*TER T*LL* / *O***E **LKER
228. Original; crime family consigliere; killed by boss' daughter ***K **L**T*
229. Original; student; accidentally electrocuted by unconscious friend D*R** K**
230. Original but distant relative of comics based character; robotics engineer; seen in 2147 *R**E
231. Original; federal agent posing as accountant; killed by villainous cast character J**K*O* KL*****H
232. Original; government agent; from China but killed in New Zealand *E* ***G
233. Original; waitress; sister-in-law and ex-girlfriend of major character **RL* D*GGLE
234. Original; criminal; broken out of jail by super-villain girlfriend *L** **RKER
235. Comics, though possibly created for earlier show; police task force officer; romantically involved with super-villain; Batman RE*EE *O*TO**
236. Original; high school coach; allowed main character to be assistant coach G***E*
237. Comics; police commissioner; disapproved of main character's actions; Green Arrow *R*** *UDO*ERDO
238. Mostly comics (real name original but related to character from comics); bank robber; son of #198 **E / K*LE RE*TO*
239. Original; unrevealed; husband of long recurring character RO*  [LOCKED; characters found at time of locking: EFGHJKORT345]
240. Comics (comics version has different surname); unrevealed; son of cast character; Adventures of Superman *D** FO*TER
241. Comics (comics version has different surname); legal aid attorney; was the best friend of a cast character; Green Arrow  JO**** DE L* *EG*
242. Comics; high ranking military officer; trained a main character; 52 **O FE* GULO*G
243. Comics; mobster/money launderer, nightclub manager; managed the nightclub on behalf of a super-villain; Detective Comics  JOH*** ****T**O
244. Original; SWAT officer turned bodyguard; briefly replaced a major character in job  RO* **OTT
245. Original; federal agent; possessed by villain based on comics hero  DO*O***
246. Earlier version of character; earlier version has code name from comics that this version doesn't share; head of security, criminal; killed by anti-matter RE*E R***RE* (E*RTH-#)
247. Comics; gangster; can turn his body into a specific element GOLDF**E / KE*TH
248. Original; unrevealed; mother of #122 *** L*
249. Comics; trivia night host; comics version is a major villain; Action Comics  O***LD LOO***
251. Real person; shogun; died ten years prior to real world version  TOKUG*** *E**T*U
252. Original; high priestess; prisoner whose name was used for prison   J**D*H KOL RO**
253. Original; board member; got major character ousted from company they were running DE****
255. Original; unrevealed; lives in a Maritimes city *EGG* ****O*
256. Original; shopkeeper; active in the near future  FEL**
257. Comics (somewhat different name); assassin; second in command in her organization; Batwoman: Rebirth  T*T****
258. Comics; military Lieutenant Colonel working for major character; Human Defense Corps    RE*O RO*ETT*
259. Original; unrevealed; father of #122 LLO** L*
261. Original; criminal turned boxer; wrongly suspected of being a super-villain  F**T / *HR** *EDLO*K
262. Comics but different name; hitman; hired to spy on main character; Superman D***D FUGLE*T*D
263. Earlier show (different real name); drug dealer; ex-lover of main character; Batman: The Animated Series **** DOLL / **GEL**UE **RT**
264. Original; bank robber; has fire powers ER*K FR*E
265. Comics; apparent criminal; can generate acid; Action Comics ***D ***TER / *H*L** ***TER
266. Comics (comics version unnamed); unrevealed; ex-mistress of #313; unsure, possibly New Year's Evil: Prometheus ****D* *E*TF*ELD
267. Original; unrevealed, possibly none; engaged to a guy but secretly in love with a woman **. ****L**R
268. Original; probably none so far, possibly student; foster daughter of major characters  E**E
270. Original; parole officer for main character *U*** *TE*E**
271. Original; member of resistance group; extra-terrestrial *'KE**
272. Comics; probably criminal; extra-terrestrial convict; Superman **RTO*
273. Original; car thief who claimed that a cast character was trying to steal his car  EL* [LOCKED; characters found at time of locking: EFGHJKLORTU3457]
274. Original; soldier; father of cast character J**E* J**K*O*
275. Original; soldier turned leader of vigilante group inspired by main character *GL**
276. Comics; toy manufacturing company owner; ex-boss of super-villain; Action Comics *HE*TER DU*HOLT*
277. Original; senator with an interest in extra-terrestrials  GR***ERR*
278. Original; EMT; could swap people's DNA *ELT**G *O**T / **TTHE* K**
279. Original; attorney; did pro-bono work for compAny major character worked at ****T****
280. Comics; personal physician for major villain; Superman's Pal, Jimmy Olsen D***E* DO*O***
281. Original; philanthropist/clinic owner; wife of major character, mainly seen in photo RE*E*** *ERL**
283. Real person; student when last seen; likely later an attorney, philanthropist, and civic leader; former student of major character **LL*** G*TE*, *R.
286. Comics; police detective; former work partner of major character; Green Arrow and Black Canary  LU*** H*LTO*
287. Original; influencer; disfigured subsequent to cosmetic surgery ****ERL* *R*GHT
288. Comics; Russian federal agent; investigated by an American agency; Superman: Red Son **OTR RO*LO*
289. Comics; journalist; operated in a different city pre- and post-Crisis; Adventures of Superman RO* TROU*E
290. Comics but gender swapped and comics version's real name is unknown; drug dealer; can manipulate time; Showcase TURTLE # / FR*D* *O**KO* (Since the code name is now pretty obvious, please name the real name when answering this one)
291. Original; criminal/double agent; acted as recruiter for her actual organization **** F***D
292. Original; very high ranking poiltician; predecessor killed in alien invasion *U*** *R**DE*
293. Comics (comics version has different first name); criminal; counterpart of cast character's brother; Justice League of America's Vibe  RU*TURE / D**TE R**O* (E*RTH-#)
294. Earlier character this continuity; none; VR version of cast character *LE* D***ER* (O***D*** *L*T**U*)
295. Original; banker; saved from building that was blown up  G*R*
296. Original; football coach; hid that a player has brain damage and was using steroids KURT DO*OHUE [LOCKED; characters found at time of locking: DEFGHJKLORT345790]
297. Original; mercenary; worked for cast character's mother ****E **K*LLE*
298. Comics but gender swapped thus real first name different; mechanical engineer turned criminal; uses robotic creatures; The Atom *UG-E*ED ***D*T a.k.a. *UEE* *EE / *R*E L*R***
299. Comics; assassin/black ops agent; deserted federal agency she used to work for; Detective Comics  O*** *****
301.  Somewhat based on comics (gender swapped), though another character has the comics version's abilities; quantum engineer/CEO; was replaced by a doppelgänger who posed as her; Animal Man  E** ***ULLO*H
302. Original; police officer; betrayed his PD to a super-villain JO*E*
303. Original; student; wore homemade costumes based on main character  L**R*
305. Original; high school student seeking university admission HE*R* *EU***
306. Possible gender swapped version of character from earlier show; biomedical engineer, CEO; mother of cast character; The Flash (1990-1991 series) **RL* T***H*U*ER
307. Comics; criminal; wrongly imprisoned for false confession; Supergirl *UR*UR / ***H*EL ***R
308. Original; mixed martial arts fighter; affected by a totem being activated *GOR *T*RRO*
309. Original; waitress; dropped food and drinks after bumping into co-worker  TR***
310. Original; singer; from Old West *O**O* **RR*TOR
311. Original; computer hacker; seduced by someone who killed him  K*R** **TE*
312. Original; fence; tried to steal from jewel thief **** DERE***K
313. Comics (but this name not used in comics); CEO; masterminded an outbreak of tuberculosis; Vigilante  JU*T** *L***OUR*E
314. Comics; unrevealed if applicable; demonic rival to cast character; Hellblazer **L**R****
315. Original; criminal; worked for comics-based villain  EDD*E **L**K
316. Original; museum curator; super-villain stole necklace she had obtained permission to exhibit *O*****
317. Original; maid; murdered by employer  G*L*** *E*ED*KTO*
318. Original; shop owner; aunt of super-villain ***E*D
319. Original; drug dealer; sold drugs to cast character  JORD** KER*
320. Original; artifacts collector; attacked by super-villain **R**TO*H ***K*
321. Original; unrevealed; possible professional fighter; part of super-villain's fight club *U*LL
322. Original; reverend; arrested villager accused of being a witch **R*O**
323. Original; judge; helped send prisoners to death row regardless of guilt or innocence  R***O*D **L*ER**K
324. Original; unrevealed; was once a potential date for cast character via dating ap *HR** H***ER
325. Likely comics (not DC), different surname; probable student when last seen; went drag racing with boyfriend; Pep Comics *ETT* *E**ER
326. Original; military sergeant; part of army strike team **TE*
327. Original; adventurer; current cast character **OO*ER / E**ER**** *RU*
328. Original; asylum nurse; informed by main and other cast character she was in danger but she realized they weren't entirely telling the truth  T****
329. Original; some sort of information provider; member of a shadow organization  LE***TH** *E**E*GER
331. Original; criminal agent; leader of group within a group *L**RE*
333. Original; criminal; prison bunk mate for recurring character *O TR****
337. Original; criminal/car workshop owner; killed by someone he tried to blackmail D***EL *URGE
338. Original; serial killer; her son was intially believed by heroes to be the killer *RO* **GHT *L**HER / K*TH* *E*ER*
339. Comics; bank robber/terrorist; electricity powers; All-Star Squadron DE*TH*OLT / J*KE ****O**
340. Comics; high priestess; Egyptian who died thousands of years ago; Flash Comics *H**-*R*
341. Comics but spelled slightly differently; village leader; ancestor of a major character; Hellblazer KO**TE*T**
342. Original; probable student when last seen; boyfriend of  #325  TO*** FULLER
343. Comics; jewel thief; bonded with alien symbijo*ote; Action Comics *E**GER*E / ***EL* FERRER
344. Original; unrevealed; father of #255  TO***
345. Original; mayor; killed by hero's imposter *EL** ***TLE
346. Original; unrevealed; asked reporters to help locate missing son *H*RO* *O*ELL
347. Original but related to character from comics; physics professor/philanthropist/criminal/engineering professor; wife of major villain  **RL**E DE*OE
348. Original; scullery maid; lover of #267 ELLE* [LOCKED; characters found at time of locking: EFGHJKLORTU3457]
349. Comics but gender swapped, so slightly different first name; physical therapist; divorced from cast character; Spectre ***L HOLT
350. Original; police technician; required to review footage involving main character  KELTO* [LOCKED; characters found at time of locking: EFGHJKLORTU3457]
351. Original; prison officer; was fired  L*RR* *H*****
352. Original; high ranking military officer/government agent/criminal; watched cage fight *LE** *URO*
353. Comics, though heavily changed; bodyguard/criminal; arrested for murder; World's Finest Comics **KO*
354. Original; unrevealed; #274's wife JEFFER*O* J**K*O*'* *OTHER
355. Original, though name might be a nod to two real life people; mayor; surname may refer to actor who was in another Arrowverse show GEORGE DE**
356. Original; unrevealed; was devastated when ex-wife was murdered ***RLE* EKED
357. Original; criminal; worked for two different bosses (not concurrently) GREG O**OR*E
358. Original; crime boss employee; killed by boss' daughter ***L *O****
359. Original; criminal; part of Chinese crime family L* KHU** HU*
360. Comics, though different but similar real first name; photographer/thief; drawn to shiny objects; The Man of Steel **G**E / **RGOT
361. Original; scientist; tasked to recreate a virus  RO**RT *O*G
362. Original; member of secret, arguably criminal organization; friend turned enemy of major character ***** DRU*E
363. Comics; hypnotist; worked for major villains; Teen Titans  E**G** / E*EL** RH**E
364. Original; soldier/mercenary; hired to bomb waterfront *LOOD**ORT / RO*ERT DU*O**
366. Original; student; helped beat up cast characters  T**** R***
367. Original; reporter; cast character **LL*** DE*

 

Adding letters/number to answers as chosen by Random Number Generator. Letter (*) and number (#) patterns below. If there is a forward slash, the first name is the code name and the second name is the real name (for such characters I'll accept either name).  Not every number appears in this collage but every letter does. Obviously if a letter is revealed but not shown for a particular character, they don't have that letter in their name.

The next letters and numbers, in order, are B, Z, and 1.

Letters/numbers used so far: BDEFGHJKLORTZ13457890

1. Comics; criminal; former classmate of two cast characters; Action Comics R**K **L*ER*E
4. Original; unrevealed; girlfriend of one villain who was killed by another ZOE* [LOCKED; characters found at time of locking: BDEFGHJKLORTZ345790]
5. Comics; unwilling drug producer; powers related to his tears; Master Comics  THE *EE*ER
6. Original; university dean; ally of a hate group **RRE*
10. Comics; businessman; related to a reformed villain; The Flash  O*GOOD R*TH****
12. Original; cultist; become disillusioned with source of worship  OL****
16. Original; police detective; in sole appearance directed a main character to someone's office *DD*E
17. Original; unrevealed; mother of kidnap victim REG*** **LL****
18. Comics; criminal; insecure re: physical appearance; Batman Family DUEL* DE*T
19. Comics; warden; sold meta-humans to villain; The Flash: Iron Heights GREGOR* *OLFE
20. Comics; terrorist; leads group attempting to blow up city; Green Arrow *ERO**** D*LE
21. Comics; crime lord; one of four remaining leaders in his org surviving after a purge; Green Arrow **RU* BRODER**K
22. Comics; mayor; wounded by a bullet during a riot; Batman: Turning Points  ***H*EL *K***
23. Original; scientist; originally from 1925 but now time travelling; cast character G*** D***E*
24. Original; editor-in-chief; believed main character had gone bad **OTT E****
25. Comics; scientist turned criminal; infected by alien parasite; Firestorm **R***TE / RUD* JO*E*
26. Original; criminal; member of China-based crime group  K*T*U *HE*G
27. Original but related to comics based character; sheriff; abandoned daughter upon learning she was a lesbian  O***R ROD**
29. Original; federal agent; electrocuted TO** K**
31. Original; drug dealer; drug his sold turned people into monsters JERR* **LLER
32. Original, but uses comics character as alias; businessman; half-brother of a main character *ORG** E*GE / T*L-RHO
33. Original; engineer turned professor; murdered by a super-villain  L**D*** K**G
34. Original; marine turned bodyguard/criminal; killed by a main character to save an ally ***L K*O*
35. Original; would-be unwilling slave; daughter of #17 *ZZ* **LL****
36. Comics; unrevealed; murdered by her husband; New Teen Titans DOR** *H**E
37. Original; attorney; killed by a vigilante GU* **B*TO**
38. Original; computer engineer/programmer; used VR as a means of torture R**H*RD B*TE*
39. Comics; military general; father of counterpart of a main character; Superman's Girl Friend, Lois Lane *** L**E (E*RTH-TU*##)
40. Original; university professor; betrayed her sister **E*E **L
41. Original; unrevealed; given age, possible student at some point, otherwise none; son of a main character JO***
42. Original; assassin; committed suicide to avoid further interrogation THE **KE
46. Original; sheriff; active in 1925 THO*** *OOD
51. Comics; unrevealed; mother of hero active in the future; Green Arrow **DR* H**KE
52. Webseries (different first name); police department employee; super-villain's sister in law; Gotham Girls  DEE ***TH*
54. Comics; owner/leader of a branch of a company; father of a cast character; Superman Annual  BER**RDO ROJ**
55. Comics; bodyguard turned "church" leader; succeeded a super-villain in a comics tie-in; Animal Man *L**TO* HOGUE
56. Original; unrevealed; possible housewife; mother of a main character DOROTH* HE**OOD
57. Original; criminal; henchman to a villain who is the son of a reformed villain **L**DER
58. Original; alderman; kidnapped and killed by villain for revenge R**H*RD FORD
60. Original; criminal; alcoholic who abused his ex-girlfriend ***H*EL ***O**
61. Comics; firefighter turned arsonist; murdered people he felt had abandoned him; Detective Comics G*RF*ELD L****
62. Original; security agent; helped keep a protest from going further out of control *B*R* [LOCKED; all remaining letters the same; characters found at time of locking: BDEFGHJKLORT345790]
64. Comics; criminal; could shrink objects; The All-New Atom D**RF*T*R / **LBERT RU*D**E
65. Original; chef (police officer in another timeline); killed in revenge for actions from temporary timeline *TU*RT HOLZ***
66. Original; student when last seen; friend/classmate of major character **RGO
67. Comics; bank robber; has psychic powers; Daring New Adventures of Supergirl *** / G**LE **R*H
69. Original; unrevealed; drug addict, wife of major character  L*UR* R***REZ
70. Original; likely assassin; killed over 200 people T*GRE***
71. Comics but with different first name as comics version's first/last name taken by different character; unrevealed; was the wife of a major character; Showcase **** LOR**G
72. Original; unrevealed; part of family cheated out of life's savings  ER** *OORE
74. Comics, though comics version is unnamed; soldier; father of major villain; unsure, possible The Flash Secret Files and Origins J**E* ZOLO*O*
75. Character's race based on single comics character; criminal  U****ED HELLGR****TE
76. Comics characters use code name but none seem to be the basis of this character; criminal; prison escapee *H**ER*
77. Original; unrevealed; mother of major character DEBB*E D*B**
78. Comics; businessman/terrorist; part of a plan to rid the Earth of most of humanity; Green Arrow **LO *R**T*GE
79. Original; politician in some sort of position of power; invited major characters on opposing sides to be keynote speakers in a media summit. ***OR OF **T*O**L **T*
80. Original; medical doctor; treated main character for free in support of their actions LO*KH*RT
81. Original; pianist; from artificial reality GR*D*
82. Original; unrevealed; patient at major character's clinic ***TT*KER
83. Original; political strategist turned chief of staff; assisted in major character's political campaign *LE* D****
84. Original; unrevealed; parent of major character Z*R* T*R*Z*'* F*THER
85. Original; businessman; embezzled about $30 million from a pension plan **R*U* RED*O*D
86. Original; serial killer; drowned victims before dressing them up DOLL**KER aka BROKE* DOLL K*LLER / B*RTO* **TH** (since the code names are now obvious, I'll need the real name with the answer)
87. Original; CEO; from Markovia *LE* T*RKO*
88. Original; criminal; helped rob seven banks in three states within two weeks *KULL *** / R**K*E JE*K***
89. Original; councilman; opposed a request from a major character, fearing for his city's survival JUL-U* [LOCKED; characters found at time of locking: EFGHJKLORTU3457]
90. Original but related to character from comics; likely prince; sister was a major villain BR**L*
91. Original but deliberately made to look like unrelated Arrowverse character; mobster; from same artificial reality as #81 D*G** FO**' HU*B**D
92. Comics; king; father of #90; Superman Family **D K**G / BR**Z
93. Imposter of character somewhat but not entirely based on comics; assassin; artificial lifeform **R* L***E (RO*OT)
94. Real person; prince; reincarnated after death KH*F* [LOCKED; both remaining letters the same; characters found at time of locking: FGHJKORT345]
95. Original; unrevealed; daughter has alien pet *L***'* F*TH*ER
96. Original but relative of character from comics; engineer; father of major character *U*** *. RU*K
97. Original; prison guard; brought in as part of prison reform effort  FELTO* [LOCKED; characters found at time of locking: EFGHJKLORTU3457]
98. Original; pilot; father of close friend of major character ***D* ***O*E'* F*THER
99. Original; some sort of media employee; major character did compositions for him  H***H*
100. Original; drug dealer; stopped as part of an effort to show someone a better way in dealing with criminals **THO** *E*Z*
101. Comics; unrevealed; wife of a villain; Deadshot *U**E L**TO*
102. Original; crime boss; at attempt to kill him happened in an arena **KH**L *ETRO*
103. Real person; singer; this version wrote a song after seeing a character get abducted D***D BO**E
105. Comics; bar owner; some of his customers were killed in a weapons test; Lobo *L *R**E
106. Original; documentary director; accompanied major characters to Russia  KE*** H*RR**
108. Original; retail manager; major character briefly worked for him **L
109. Comics; former criminal of sorts; courted a major character; Superman ***Z*TLK
110. Comics; cage fighter; fought main character in a match; Adventures of Superman DR**G* [LOCKED; all remaining letters the same; characters found at time of locking: DEFGHJKLORT345790]
112. Original apparently, though comics characters with same name have appeared; assassin; hired to kill a mayor *****T*R
114. Original; disc jockey/assassin; DJ work was for a major character *H**E
116. Original; ex-criminal; extra-terrestrial  ORL**DO D****
117. Comics; attorney; represented main character in trial; Showcase JE** LOR**G
118. Original; CEO/businessman/land baron; used company to swindle hundreds out of their homes and life savings *D** HU*T
119. Original; councilman; tried to get a bribe from father of main character  HE*R* GOOD***
121. Original; federal law enforcement agent; investigated main character *****D* **T*O*
122. Original; student when last seen; history changed significantly due to the Crisis  KE*** L*
124. Original; soldier (private); killed as part of a plan to frame someone in the theft of weapons *OLL***
125. Original; time pirate; erased from history due to future deeds  K**LE* DRUZ**
126. Original but related to character from comics; in one timeline was a hero's adoptive father *HU*K ****BE
127. Original; toy shop worker; mother of a cast character **R* **GO***
128. Original; unrevealed; with husband, acted as guardian for grandson after grandson's parents were killed T**LOR *OORE'* GR**D*OTHER
129. Original; temporal agent; hypnotized during a performance review DE*TEL [LOCKED; characters found at time of locking: DEFGHJKLORT345790]
130. Likely comics;  military general; taken hostage during weapons demonstration; All-American Men of War *LOUD [LOCKED; characters found at time of locking: DEFGHJKLORT345790]
131. Comics (slightly different surname); criminal; can manipulate people's emotions; The Flash R***BO* R**DER     / RO* B**OLO
132. Original; nightclub employee; made out with a guy has part of the latter's attempt to break up with his girlfriend BE*K*
133. Original; student; plays high school football **L*OL* TE*GUE
134. Comics, though names may or may not be the same; unrevealed; active as such in the Old West; Weird Western Tales *H**-*R*'* 19TH *E*TUR* RE****R**T*O*
135. Comics; unrevealed; mother of a main character; Detective Comics G*B* K**E
136. Comics; travel enforcement officer; has telepathy and other powers of the mind; Mister Terrific BR****TOR* / DO***** L***E
137. Original; medical doctor/slave trader; sent humans off world ***LDOR*** DO*TOR
138. Original; student; dated a cast character *H**E *OL***
139. Original; fire chief; targeted by #61  R***E*
140. Original; CEO/businessman; hired an assassin to kill bidders of a company he wished to own **RR* **TEL
141. Original; personal assistant; posed as his employer (a major villain) to help them escape another major villain D***E* D*RHK'* *****T**T
142. Original; restaurant employee; own name unknown but restaurant name refers to something you might find on a table at a restaurant T*BLE **LT HO*TE**
143. Original; real estate developer; people died in his buildings due to inadequate heating J*H* ***KEL
144. Original; career criminal; took over boyfriend's criminal business why he was incarcerated ******
147. Comics; board member; tried to use company owner's emails to ruin her reputation; Superman: The Man of Steel D*RK *R**TRO*G
148. Original (real name), comics (aliases); vigilante; hero active in the future on a parallel Earth; Green Arrow GREE* *RRO* a.k.a. *O**OR H**KE /  JOH* D*GGLE, JR. (E*RTH-1#)
149. Original; unrevealed; clubber who used drugs *ERO**** ***RK*
150. Original; criminal; injured himself shooting someone he didn't know had powers. U****ED *UGGER
151. Comics character with different name; warrior; active in the 31th century in one future under a different name; Legion of Super-Heroes *E*T*LE**E
152. Original; unrevealed; broke up with girlfriend for cheating on her E**L*
153. Real person; astronaut; real version still alive as of Feb 2022  FRE* H***E
154. Original; some sort of bearer (I can't be much more specific without revealing the answer); first of their kind (connected to other bearers)  F*R*T ***R*T TOTE* *E*RER
155. Comics but gender swapped (real names may or may not be similar); arsonist; briefly acquitted when issues arose in his trial but arrested again after another crime; Justice League Task Force HE*T *O*GER / LU**OU* *OOL*DGE
156. Original; high ranking fishing boat worker; brought a main character home after time away ***T***
157. Original; board member; killed by some sort of robotic tech *H*L
158. Comics; businessman; took over a major character's body; Underworld Unleashed *ERO* [LOCKED; both remaining letters the same; characters found at time of locking: EFGHJKORT345]
159. Original; police officer; held captive for a time in another world D**** KORBER
160. Original mixed with mythology; coachman; replaced a Hindu god  K***DE** / *U*J**
162. Original; district attorney; represented a case against a main character *** *R***D
163. Original; unrevealed, but likely student if any when last seen; father falsely charged with the murder of her mother *ZZ* DE*L**
164. Original; student when last seen; star high school quarterback J*KE HO*ELL
165. Original; criminal; killed by his boss  ROBERT B**LOR
166. Comics; police detective; cast character and romantic interest to another cast character; Superman **GG*E ****ER
167. Original; Unrevealed, possible criminal; prisoner on a ship  HE*DR**K *O* *R***
169. Comics (real names may or may not be the same), cryogeneticist, bartender, criminal; romantic interest to cast character; The Flash Annual *H*LLBL***E / **RK BL***E
170. Original; deputy sheriff; in one timeline investigated #122's death *LE*E**
173. Original but related to character from comics; unrevealed; twin sister of a key recurring character *E*
174. Original; terrorist; tried to stop the launch of a VR service *** ****H*RE
175. Original; marine biologist; widow of the counterpart of a super-villain T**** L**DE*
176. Original but surname is a nod to real person; babysitter for the child of a super-villain *UELLER  [LOCKED; characters found at time of locking: EFGHJKLORTU3457]
177. Original; judge; presided over main character trial  H**KER*O*
178. Original but successor to comics based character; first and last names are nods to two different real people; collections officer; can manipulate people's emotions R***BO* R**DER #.0 / **RR*E B*TE*
180. Original; nun turned singer/guitarist; part of a band that a cast character is also part of G*LL*
182. Original; fence; arrested during the sale of a stolen jewel *L**RE *BBOTT
184. Comics; board member, businessman; saved from assassination attempt by a main character; Steel TO* *E*TO*
185. Original; lawyer turned criminal; sought revenge against the lawyer firm *RTHUR **LL**
186. Movie; witch; survived her reality being destroyed by the Crisis; Supergirl *ELE** (E*RTH-TUD17)
187. Comics; wrestler turned criminal; other than a fang, thus far only seen in photo; Detective Comics K*LLER *RO* / ***LO* JO*E*
188. Original; unrevealed; extra-terrestrial BR***
189. Comics; student; aged at accelerated rate; The Flash: The Fastest Man Alive GR*FF** GRE*
190. Original; criminal; snapped after family killed in a mall J**E* EDLU*D
191. Original but surname possible nod to real person; physician; often helped main character and allies EL*** **H**RTZ
193. Original; orphanage head, foster mother; raised a major character **R* ****ER
194. Original; bowler; extra-terrestrial or at least operates outside of Earth *ER*E THE *UR*E
195. Original; police sergeant; briefed main characters on missions  F. B**G*LE*
196. Original; criminal; attended crime family gathering *ERG*O E****OZ*
197. Original; probable student; dated a cast character for a time  EL*Z*
198. Original but related to character based on comics and is more or less a stand-in for a code name she apparently didn't use; bank robber; part of family of criminals *R*. RE*TO*
199. Original; medical doctor; treated a cast character  K**L**
200. Original; nurse; worked for cast character ***
202. Original; bartender; ex-girlfriend of cast character D*RL* * [LOCKED; both remaining letters the same; characters found at time of locking: DEFGHJKLORT345790]
203. Original; unrevealed, possible student when last seen; could heal mortal injuries  FER***DO
207. Original; soldier; helped brother steal weaponry from military base  EZR* B*R*E*
208. Real person (at least going by first name); unrevealed; sought autograph from heroes **R*`
209. Comics; energy source; has strong connection to a major character; The Flash **EED FOR*E
210. Original, though shares name with comics character; unrevealed; once erroneously believed to have killed a major character *KEL [LOCKED; characters found at time of locking: EFGHJKLORTU3457]
211. Original; bank robber; sent to steal for comics based villain *ERTO [LOCKED; characters found at time of locking: EFGHJKORT345]
212. Original; criminal; prisoner in other dimensional realm ***R
214. Original; therapist for main character **LE*
215. Original but related to character from comics; fire chief; wife has launched campaign for mayor; cast character K*L* *U*H**G
216. Original; religious figure (can't say what kind without revealing name), possible assassin; officiates rituals and ceremonies THE *R*E*TE**
217. Original; sheriff; lived in Oregon BUD ELL**O*
218. Original though code name used by comics characters; crime lord; wanted to create coalition of crime gangs  TOB*** *HUR**
219. Original; criminal; joined major villain's army  R***ED
220. Original, though nicknamed by another character after a literary character; criminal of sorts, though possibly not by occupation; tormented major character for years **BEL **RT*R*GHT
222. Original; pirate; lover of famous pirate ***E *UEE*
223. Original; film director; did documentary on main character **R*** *EDO**TZ
224. Comics; outlaw; responsible for town's destruction; Weird Western Tales *UE*T** TUR*BULL
225. Comics; student; related to a main character; Convergence: Superman JO**TH** KE*T (*O*T-*R***)
226. Original; unrevealed; posed as treasure seeker in VR reality  TRE**URE HU*TER T*LL* / BO***E **LKER
228. Original; crime family consigliere; killed by boss' daughter ***K **L**T*
229. Original; student; accidentally electrocuted by unconscious friend D*R** K**
230. Original but distant relative of comics based character; robotics engineer; seen in 2147 BR**E
231. Original; federal agent posing as accountant; killed by villainous cast character J**K*O* KL*****H
232. Original; government agent; from China but killed in New Zealand *E* ***G
233. Original; waitress; sister-in-law and ex-girlfriend of major character **RL* D*GGLE
234. Original; criminal; broken out of jail by super-villain girlfriend *L** **RKER
235. Comics, though possibly created for earlier show; police task force officer; romantically involved with super-villain; Batman RE*EE *O*TO**
236. Original; high school coach; allowed main character to be assistant coach G***E*
237. Comics; police commissioner; disapproved of main character's actions; Green Arrow BR*** *UDO*ERDO
238. Mostly comics (real name original but related to character from comics); bank robber; son of #198 **E / K*LE RE*TO*
239. Original; unrevealed; husband of long recurring character RO*  [LOCKED; characters found at time of locking: EFGHJKORT345]
240. Comics (comics version has different surname); unrevealed; son of cast character; Adventures of Superman *D** FO*TER
241. Comics (comics version has different surname); legal aid attorney; was the best friend of a cast character; Green Arrow  JO**** DE L* *EG*
242. Comics; high ranking military officer; trained a main character; 52 **O FE* GULO*G
243. Comics; mobster/money launderer, nightclub manager; managed the nightclub on behalf of a super-villain; Detective Comics  JOH*** **B*T**O
244. Original; SWAT officer turned bodyguard; briefly replaced a major character in job  ROB **OTT
245. Original; federal agent; possessed by villain based on comics hero  DO*O***
246. Earlier version of character; earlier version has code name from comics that this version doesn't share; head of security, criminal; killed by anti-matter RE*E R***REZ (E*RTH-#)
247. Comics; gangster; can turn his body into a specific element GOLDF**E / KE*TH
248. Original; unrevealed; mother of #122 *** L*
249. Comics; trivia night host; comics version is a major villain; Action Comics  O***LD LOO***
251. Real person; shogun; died ten years prior to real world version  TOKUG*** *E**T*U
252. Original; high priestess; prisoner whose name was used for prison   J**D*H KOL ROZZ
253. Original; board member; got major character ousted from company they were running DE****
255. Original; unrevealed; lives in a Maritimes city *EGG* B**HO*
256. Original; shopkeeper; active in the near future  FEL**
257. Comics (somewhat different name); assassin; second in command in her organization; Batwoman: Rebirth  T*T****
258. Comics; military Lieutenant Colonel working for major character; Human Defense Corps    RE*O RO*ETT*
259. Original; unrevealed; father of #122 LLO** L*
261. Original; criminal turned boxer; wrongly suspected of being a super-villain  F**T / *HR** *EDLO*K
262. Comics but different name; hitman; hired to spy on main character; Superman D***D FUGLE*T*D
263. Earlier show (different real name); drug dealer; ex-lover of main character; Batman: The Animated Series B*B* DOLL / **GEL**UE **RT** (since the code name is now obvious, I'll need the real name with the answer)
264. Original; bank robber; has fire powers ER*K FR*E
265. Comics; apparent criminal; can generate acid; Action Comics ***D ***TER / *H*L** ***TER
266. Comics (comics version unnamed); unrevealed; ex-mistress of #313; unsure, possibly New Year's Evil: Prometheus ****D* *E*TF*ELD
267. Original; unrevealed, possibly none; engaged to a guy but secretly in love with a woman **. ****L**R
268. Original; probably none so far, possibly student; foster daughter of major characters  E**E
270. Original; parole officer for main character *U*** *TE*E**
271. Original; member of resistance group; extra-terrestrial *'KE**
272. Comics; probably criminal; extra-terrestrial convict; Superman **RTO*
273. Original; car thief who claimed that a cast character was trying to steal his car  EL* [LOCKED; characters found at time of locking: EFGHJKLORTU3457]
274. Original; soldier; father of cast character J**E* J**K*O*
275. Original; soldier turned leader of vigilante group inspired by main character *GL**
276. Comics; toy manufacturing company owner; ex-boss of super-villain; Action Comics *HE*TER DU*HOLTZ
277. Original; senator with an interest in extra-terrestrials  GR**BERR*
278. Original; EMT; could swap people's DNA *ELT**G *O**T / **TTHE* K**
279. Original; attorney; did pro-bono work for compAny major character worked at ****T****
280. Comics; personal physician for major villain; Superman's Pal, Jimmy Olsen D*B*E* DO*O***
281. Original; philanthropist/clinic owner; wife of major character, mainly seen in photo REBE*** *ERL**
283. Real person; student when last seen; likely later an attorney, philanthropist, and civic leader; former student of major character **LL*** G*TE*, *R.
286. Comics; police detective; former work partner of major character; Green Arrow and Black Canary  LU*** H*LTO*
287. Original; influencer; disfigured subsequent to cosmetic surgery ***BERL* *R*GHT
288. Comics; Russian federal agent; investigated by an American agency; Superman: Red Son **OTR RO*LO*
289. Comics; journalist; operated in a different city pre- and post-Crisis; Adventures of Superman RO* TROU*E
290. Comics but gender swapped and comics version's real name is unknown; drug dealer; can manipulate time; Showcase TURTLE # / FR*D* *O**KO* (Since the code name is now pretty obvious, please name the real name when answering this one)
291. Original; criminal/double agent; acted as recruiter for her actual organization **** F***D
292. Original; very high ranking poiltician; predecessor killed in alien invasion *U*** BR**DE*
293. Comics (comics version has different first name); criminal; counterpart of cast character's brother; Justice League of America's Vibe  RU*TURE / D**TE R**O* (E*RTH-#)
294. Earlier character this continuity; none; VR version of cast character *LE* D***ER* (OB**D*** *L*T**U*)
295. Original; banker; saved from building that was blown up  G*R*
296. Original; football coach; hid that a player has brain damage and was using steroids KURT DO*OHUE [LOCKED; characters found at time of locking: DEFGHJKLORT345790]
297. Original; mercenary; worked for cast character's mother ****E **K*LLE*
298. Comics but gender swapped thus real first name different; mechanical engineer turned criminal; uses robotic creatures; The Atom BUG-E*ED B**D*T a.k.a. *UEE* BEE / BR*E L*R***  (since the code names are now obvious, I'll need the real name with the answer)
299. Comics; assassin/black ops agent; deserted federal agency she used to work for; Detective Comics  O*** *****
301.  Somewhat based on comics (gender swapped), though another character has the comics version's abilities; quantum engineer/CEO; was replaced by a doppelgänger who posed as her; Animal Man  E** ***ULLO*H
302. Original; police officer; betrayed his PD to a super-villain JO*E*
303. Original; student; wore homemade costumes based on main character  L**R*
305. Original; high school student seeking university admission HE*R* *EU***
306. Possible gender swapped version of character from earlier show; biomedical engineer, CEO; mother of cast character; The Flash (1990-1991 series) **RL* T***H*U*ER
307. Comics; criminal; wrongly imprisoned for false confession; Supergirl *UR*UR / ***H*EL ***R
308. Original; mixed martial arts fighter; affected by a totem being activated *GOR *T*RRO*
309. Original; waitress; dropped food and drinks after bumping into co-worker  TR***
310. Original; singer; from Old West *O*BO* **RR*TOR
311. Original; computer hacker; seduced by someone who killed him  K*RB* B*TE*
312. Original; fence; tried to steal from jewel thief **** DERE***K
313. Comics (but this name not used in comics); CEO; masterminded an outbreak of tuberculosis; Vigilante  JU*T** *L**BOUR*E
314. Comics; unrevealed if applicable; demonic rival to cast character; Hellblazer **L*BR****
315. Original; criminal; worked for comics-based villain  EDD*E **L**K
316. Original; museum curator; super-villain stole necklace she had obtained permission to exhibit *O*****
317. Original; maid; murdered by employer  G*L*** *E*ED*KTO*
318. Original; shop owner; aunt of super-villain ***E*D
319. Original; drug dealer; sold drugs to cast character  JORD** KER*
320. Original; artifacts collector; attacked by super-villain *HR**TO*H B**K*
321. Original; unrevealed; possible professional fighter; part of super-villain's fight club *U*LL
322. Original; reverend; arrested villager accused of being a witch **R*O**
323. Original; judge; helped send prisoners to death row regardless of guilt or innocence  R***O*D **L*ER**K
324. Original; unrevealed; was once a potential date for cast character via dating ap *HR** H***ER
325. Likely comics (not DC), different surname; probable student when last seen; went drag racing with boyfriend; Pep Comics BETT* *E**ER
326. Original; military sergeant; part of army strike team B*TE*
327. Original; adventurer; current cast character **OO*ER / E**ER**Z* *RUZ
328. Original; asylum nurse; informed by main and other cast character she was in danger but she realized they weren't entirely telling the truth  T****
329. Original; some sort of information provider; member of a shadow organization  LE***TH** *E**E*GER
331. Original; criminal agent; leader of group within a group *L**REZ
333. Original; criminal; prison bunk mate for recurring character BO TR****
337. Original; criminal/car workshop owner; killed by someone he tried to blackmail D***EL BURGE
338. Original; serial killer; her son was intially believed by heroes to be the killer *RO* **GHT *L**HER / K*TH* *E*ER*
339. Comics; bank robber/terrorist; electricity powers; All-Star Squadron DE*THBOLT / J*KE ****O** (since the code name is now obvious, I'll need the real name with the answer).
340. Comics; high priestess; Egyptian who died thousands of years ago; Flash Comics *H**-*R*
341. Comics but spelled slightly differently; village leader; ancestor of a major character; Hellblazer KO**TE*T**
342. Original; probable student when last seen; boyfriend of  #325  TO*** FULLER
343. Comics; jewel thief; bonded with alien symbiote; Action Comics *E**GER*E / ***EL* FERRER
344. Original; unrevealed; father of #255  TO***
345. Original; mayor; killed by hero's imposter *EL** ***TLE
346. Original; unrevealed; asked reporters to help locate missing son *H*RO* *O*ELL
347. Original but related to character from comics; physics professor/philanthropist/criminal/engineering professor; wife of major villain  **RL*ZE DE*OE
348. Original; scullery maid; lover of #267 ELLE* [LOCKED; characters found at time of locking: EFGHJKLORTU3457]
349. Comics but gender swapped, so slightly different first name; physical therapist; divorced from cast character; Spectre ***L HOLT
350. Original; police technician; required to review footage involving main character  KELTO* [LOCKED; characters found at time of locking: EFGHJKLORTU3457]
351. Original; prison officer; was fired  L*RR* *H*****
352. Original; high ranking military officer/government agent/criminal; watched cage fight *LE** BURO*
353. Comics, though heavily changed; bodyguard/criminal; arrested for murder; World's Finest Comics **KO*
354. Original; unrevealed; #274's wife JEFFER*O* J**K*O*'* *OTHER
355. Original, though name might be a nod to two real life people; mayor; surname may refer to actor who was in another Arrowverse show GEORGE DE**
356. Original; unrevealed; was devastated when ex-wife was murdered ***RLE* EKED
357. Original; criminal; worked for two different bosses (not concurrently) GREG O*BOR*E
358. Original; crime boss employee; killed by boss' daughter ***L *O****
359. Original; criminal; part of Chinese crime family L* KHU** HU*
360. Comics, though different but similar real first name; photographer/thief; drawn to shiny objects; The Man of Steel **G**E / **RGOT
361. Original; scientist; tasked to recreate a virus  ROBERT *O*G
362. Original; member of secret, arguably criminal organization; friend turned enemy of major character Z**** DRU*E
363. Comics; hypnotist; worked for major villains; Teen Titans  E**G** / E*EL** RH**E
364. Original; soldier/mercenary; hired to bomb waterfront BLOOD**ORT / ROBERT DUBO**  (since the code name is now obvious, I'll need the real name with the answer)
366. Original; student; helped beat up cast characters  T**** R***
367. Original; reporter; cast character **LL*** DE*
 

Updated the clues list above to add a few overlooked letters. Beyond such oversights, I probably won't add to the clues until at least some of the easy wins are identified.

18. Duela Dent

31. Jerry Miller

58. Richard Ford

80. Lockhart

94. Khufu

187. Killer Croc/Waylon Jones

289. Ron Troupe (Earth-1)